Details of the Optogenetic Tool
| General Information of This Photoreceptor (PR) | ||||||
|---|---|---|---|---|---|---|
| PR ID | PR00006 | |||||
| PR Name | Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR) | |||||
| Source of Species | Arabidopsis thalino | |||||
| Class | Cryptochromes | |||||
| UniProt ID | Q96524 | |||||
| GenBank | NP_849588 | |||||
| PDB ID | 6X24 | |||||
| Sequence |
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSL
AHLSQSLKALGSDLTLIQTHNTISAILDCIRVTGPTKVVFNHLYDPVSLVRDHTVKEKLV ERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPEEEGQFYPG RWRLMPITAAAEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLI DYAKNSKKVVGNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRG IGLREYSRYICFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWA TGWMHNRIRVIVSSFGVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHEL DRLDNPALQGAKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKP IVDIDTARELLAKAISRTREAQIMIGAA |
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| Components | Photoreceptor | Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR) | ||||
| Complementary Protein | Cryptochrome-interacting basic-helix-loop-helix 1 (CIB1/CIBN) |
 Detail Info
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| Cofactor | Flavin adenine dinucleotide (FAD) |
 Detail Info
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| 3D Structure | ||||||
| Click to Save PDB File | ||||||
| Cofactor Detail of This PR |
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|---|---|---|---|---|---|---|
| Cofactor Name | Flavin adenine dinucleotide (FAD) | |||||
| PubChem CID | 643975 | |||||
| Structure |
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| Formula | C27H33N9O15P2 | |||||
| Molecular Weight | 785.5 | |||||
| Optogenetic System (OS) Consisting of This PR |
|---|
OS Name: Cofilin-actin interaction optocontroled regulated system (CofActor)
[1]
OS Name: genetically encoded light-inducible protein-interaction system (LIPI)
[8]
OS Name: Light activated rtTA system (Li-rtTA)
[12]
OS Name: Light induced PIP3 production system (PI3K)
[13]
OS Name: Light inducible nuclear translocation and dimerization system (LINTAD)
[14]
OS Name: Light-activated reversible inhibition by assembled trap of intracellular membranes by Rab11 (IM-LARIAT-Rab11)
[15]
OS Name: Light-activated reversible inhibition by assembled trap of intracellular membranes by Rab5 (IM-LARIAT-Rab5)
[15]
OS Name: Light-gated I-BAR (inverse BAR) domain containing tools 4 (CRYARs 4)
[16]
OS Name: Light-gated I-BAR (inverse BAR) domain containing tools 5 (CRYARs 5)
[16]
OS Name: Light-gated I-BAR (inverse BAR) domain containing tools 6 (CRYARs 6)
[16]
OS Name: Light-gated I-BAR (inverse BAR) domain containing tools 7 (CRYARs 7)
[16]
OS Name: Light-inducible cell reprogramming system (LIRE)
[17]
OS Name: Light-inducible transcriptional effectors (LITEs)
[18]
OS Name: Light-trigggered recruitment of G protein signaling protein system (LTR-RGS)
[19]
OS Name: Optogenetic control DDX4 system (OptoDDX4)
[23]
OS Name: Optogenetic control Exoc70 for membrane traffiking system 1 (Opto-Exoc70-MT 1)
[24]
OS Name: Optogenetic control FUS system (OptoFUS)
[23]
OS Name: Optogenetic control HNRNPA1 system (OptoHNRNPA1)
[23]
OS Name: Optogenetic control receptor molecules concentrate at the postsynaptic density system 1 (Opto-PSD 1)
[29]
OS Name: Optogenetic control receptor molecules concentrate at the postsynaptic density system 2 (Opto-PSD 2)
[29]
OS Name: Optogenetic control receptor molecules concentrate at the postsynaptic density system 3 (Opto-PSD 3)
[29]
OS Name: Optogenetic controlled Akt signal system (Opto-Akt)
[30]
OS Name: Optogenetic controlled C-RAF signal system (Opto-C-RAF)
[33]
OS Name: Optogenetic controlled Dab1 signal system (Opto-Dab1)
[34]
OS Name: Optogenetic controlled Focal Adhension Kinase (OptoFAK)
[35]
OS Name: Optogenetic controlled GEF signaling to regulate Ccd42 system (OptoGEF-Cdc42)
[36]
OS Name: Optogenetic controlled iTrkB signaling system1 (Opto-iTrkB1)
[37]
OS Name: Optogenetic controlled iTrkB signaling system2 (Opto-iTrkB2)
[37]
OS Name: Optogenetic controlled iTrkB signaling system3 (Opto-iTrkB3)
[37]
OS Name: Optogenetic controlled Wnt signaling system (OptoWnt)
[40]
OS Name: Optogenetic dopamine transporter multimerization system (OptoDTM)
[41]
OS Name: Optogenetic induction of caspase-8 mediated apoptosis V2 (Opto-Casp8-V2)
[42]
OS Name: Optogenetic induction of caspase-8 mediated apoptosis V2 cassette (Opto-Casp8-V2 cassette)
[42]
OS Name: Optogenetic mitochondira deformation system 1 (OptoMD 1)
[43]
OS Name: Optogenetic multiple sclerosis mechanism researching system 1 (OptoMSMR 1)
[44]
OS Name: Optogenetic multiple sclerosis mechanism researching system 2 (OptoMSMR 2)
[44]
OS Name: Optogenetic multiple sclerosis mechanism researching system 3 (OptoMSMR 3)
[44]
OS Name: Optogenetic recruit talin for integrin activation system (OptoRTIA)
[45]
OS Name: Optogenetic regulate DNA methylation system (Opto-DNAM)
[46]
OS Name: Optogenetic regulate iTrkA activity by CRY2 system (Opto-iTrkA-CRY2)
[47]
OS Name: Optogenetic regulate RhoA activity by ARHGEF11 (OptoGEF-RhoA)
[48]
OS Name: Optogenetic regulate STE5 activity system (OptoSTE5)
[49]
OS Name: Optogenetic regulated G-protein signaling system (Opto-RGS2)
[52]
OS Name: Optogentic regulate stromal interaction molecule 1 system 1 (OptoSTIM1-1)
OS Name: Optogentic regulate stromal interaction molecule 1 system 3 (OptoSTIM1-3)
[56]
OS Name: Optogentic regulate stromal interaction molecule 1 system 4 (OptoSTIM1-4)
[56]
OS Name: Photoactivated split lexA transcriptional activation system (PA-LexA)
[57]
OS Name: PIP3 production by photo-activated PI3K (PPAP1.0)
[58]
| References |
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