Details of the Optogenetic Tool

Near-infrared light-controlled systems for gene transcription regulation, protein targeting and spectral multiplexing

Near-Infrared Light-Controlled Gene Expression and Protein Targeting in Neurons and Non-neuronal Cells

Modular and Molecular Optimization of a LOV (Light-Oxygen-Voltage)-Based Optogenetic Switch in Yeast

Fungal Light-Oxygen-Voltage Domains for Optogenetic Control of Gene Expression and Flocculation in Yeast

Light-Inducible Recombinases for Bacterial Optogenetics

General Information of This Photoreceptor (PR)
PR ID	PR00081
PR Name	Vivid PAS domain (VVD)
Source of Species	Neurospora crassa
Class	LOV domain
UniProt ID	Q9C3Y6
GenBank	149243087
PDB ID	2PDR
Sequence	MSHTVNSSTMNPWEVEAYQQYHYDPRTAPTANPLFFHTLYAPGGYDIMGYLIQIMNRPNP QVELGPVDTSCALILCDLKQKDTPIVYASEAFLYMTGYSNAEVLGRNCRFLQSPDGMVKP KSTRKYVDSNTINTMRKAIDRNAEVQVEVVNFKKNGQRFVNFLTMIPVRDETGEYRYSMG FQCETE
Components	Photoreceptor	Vivid PAS domain (VVD)
Components	Cofactor	Flavin adenine dinucleotide (FAD)	Detail Info
3D Structure
3D Structure	Click to Save PDB File

Cofactor Detail of This PR
Cofactor Name	Flavin adenine dinucleotide (FAD)
PubChem CID	643975
Structure
Formula	C27H33N9O15P2
Molecular Weight	785.5

Optogenetic System (OS) Consisting of This PR

OS00149

OS Name: Blue light-controlled gene expression system (B-GE)

[1] , [2]

Fusion protein: Regulatory protein GAL4

OS00618

OS Name: Fungal lightCoxygenCvoltage system carrying Hap1p DBD (HAP-LOV)

[3]

Fusion protein: Heme-responsive zinc finger transcription factor HAP1

Recruited protein: Transcription factor p65

OS00150

OS Name: Optogenetic control gene expression by two LOV blue-light photoreceptor system (FUN-LOV)

[4]

Fusion protein: Regulatory protein GAL4

Recruited protein: Regulatory protein Gal4

OS00151

OS Name: Optogenetic control Recombinase Cre by VVD system (Opto-Cre-VVD)

[5]

Fusion protein: CreN means N terminal of Cre recombinase and CreC means C terminal of Cre recombinase

References