General Information of This Controlled Protein (CP)
CP ID CP00243
CP Name Improved Light-Inducible Dimer (iLID)
CP Type Functional protein
Common Name NPH1-1
Organism Avena sativa (Oat)
UniProt ID O49003
UniProt Entry O49003_AVESA
Sequence
LATTLERIEKNFIITDPRLPDNPIIFASDSFLQLTEYSREEILGRNCRFLQGPETDRATV
RKIRDAIDNQTEVTVQLINYTKSGKKFWNVFHLQPMRDYKGDVQYFIGVQLDGTERLHGA
AEREAVCLIKKTAFQIAEAANDEYNF
Optogenetic System (OS) Controlling This CP
OS00182
OS Info
OS Name
Light regulated signal protein localization and activity system 1
[1]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00183
OS Info
OS Name
Light regulated signal protein localization and activity system 2
[1]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00354
OS Info
OS Name
Light regulated signal protein localization and activity system 3
[1]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB (R73Q))
Cofactor
Flavin mononucleotide (FMN)
OS00355
OS Info
OS Name
Light regulated signal protein localization and activity system 4
[1]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB (R73Q))
Cofactor
Flavin mononucleotide (FMN)
OS00652
OS Info
OS Name
Opto-dHTH, an optogenetic inhibitor to completely disrupt GqGTP-PLC interactions 5
[2]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00193
OS Info
OS Name
Optogenetic control Cdc42 system
[3]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00623
OS Info
OS Name
Optogenetic control Exoc70 for membrane traffiking system 2
[4]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00192
OS Info
OS Name
Optogenetic control Rac system
[3]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00191
OS Info
OS Name
Optogenetic control RhoA system
[5], [6]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00710
OS Info
OS Name
Optogenetics of LOV domains with chemiluminescence 2
[7]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00178
OS Info
OS Name
Optogentic protein recruitment by iLID system 1
[8]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00179
OS Info
OS Name
Optogentic protein recruitment by iLID system 2
[8]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00180
OS Info
OS Name
Optogentic protein recruitment by iLID system 3
[8]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00181
OS Info
OS Name
Optogentic protein recruitment by iLID system 4
[8]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
References
1 Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins
2 Spatiotemporal Optical Control of Gq-PLC Interactions
3 Cells lay their own tracks - optogenetic Cdc42 activation stimulates fibronectin deposition supporting directed migration
4 An active tethering mechanism controls the fate of vesicles
5 Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling
6 Increasing spatial resolution of photoregulated GTPases through immobilized peripheral membrane proteins
7 Photoactivation of LOV domains with chemiluminescence
8 Optimized iLID Membrane Anchors for Local Optogenetic Protein Recruitment