General Information of This Controlled Protein (CP)
CP ID CP00404
CP Name Transmembrane domain of Miro1 (MiroTM)
CP Type Fusion protein
Common Name Mitochondrial Rho GTPase 1 (AtMIRO1) (EC 3.6.5.-) (Miro-related GTPase 1)
Organism Arabidopsis thaliana (Mouse-ear cress)
UniProt ID Q8RXF8
UniProt Entry MIRO1_ARATH
KEGG ath:AT5G27540
Function Mitochondrial GTPase required to maintain proper development, morphology and intracellular distribution of mitochondria, which in turn are essential for the progress of embryonic cell division, development of haploid male and female gametes, and pollen tube growth.
Sequence
MARYAAGAVDCPGSPKSVRIVVVGDKGTGKSSLIVAAATDSFPPNVPPVLPDYKLPIEFF
PDGIPVTIVDTSSRPEDRDIVAEELKRADAVVLTYACDRPETLERLSEYWLPELRRLEVK
IPIIVAGCKLDFRDDNNQVSLEQVMSPIMQQFREIETCIECSALKQLQAQEVFYYAQKTV
LHPTGPLFDQDSQALKPRCVRALKRIFILCDHDRDGALSEAELNDFQVKCFHAPLQPSEI
EGVKRVVQEKLPEGVNERGLTVTGFLFLHALFIEKGRLETTWTVLRKFGYNNDIRLAEEL
LPSAIFKRAPDQSFELTNAAIDFLKGMYMLFDDDQDNNLRPQEIEDLFSTAPESPWKEAP
YEDAAEKTALGGLSFDAFLSMWSLMTLLEPARSVENLIYIGFPGDPSTAIRVTRRRRLDR
KKQQCERKVFQCFVFGPNNAGKSALLNCFLGRSYTDNQESTTDERYAVNMVDESGAKKTL
IMREIPEDGVQGLFSSKESLAACDIAVFVYDSSDESSWKRATQLLVEVANYGEATGYEVP
CLMVSAKDDLDSSPISIQESTRMTQDMGIEPPVSISSKLGDFNNLFRKILTAAQHPHLSI
PETEAGKSRKHYNRLINRSLMAVSIGAAAVVVGLAAYRVYATRKSSSA
Optogenetic System (OS) Controlling This CP
OS00007
OS Info
OS Name
Optogenetic control of organelle transport system
[1], [2]
Photoreceptor (PR) Name
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
PR Info
Components
Photoreceptor
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
Complementary Protein
Cryptochrome-interacting basic-helix-loop-helix 1 (CIB1/CIBN)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00629
OS Info
OS Name
Optogenetic mitochondira deformation system 1
[3]
Photoreceptor (PR) Name
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
PR Info
Components
Photoreceptor
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
Complementary Protein
Cryptochrome-interacting basic-helix-loop-helix 1 (CIB1/CIBN)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00630
OS Info
OS Name
Optogenetic mitochondira deformation system 2
[3]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
OS00631
OS Info
OS Name
Optogenetic mitochondira deformation system 3
[3]
Photoreceptor (PR) Name
Improved Light-Inducible Dimer (iLID)
PR Info
Components
Photoreceptor
Improved Light-Inducible Dimer (iLID)
Complementary Protein
Stringent starvation protein B (SspB)
Cofactor
Flavin mononucleotide (FMN)
References
1 Optogenetic control of molecular motors and organelle distributions in cells
2 Light moves mountains in the cell
3 Light-inducible deformation of mitochondria in live cells