General Information of This Controlled Protein (CP)
CP ID CP00275
CP Name Negative Magnet (nMAG)
CP Type Functional protein
Sequence
HTLYAPGGYDIMGYLDQIGNRPNPQVELGPVDTSCALILCDLKKDTPIVYASEAFLYMTC
RSNAEVLGRNCRFLQSPDGMVKPKSTRKYVDSNTINTMRKAIDRNAEVQVEVVNFKKNGQ
RFVNFLTMIPVRDETGEYRYSMGFQCETE
Optogenetic System (OS) Controlling This CP
OS00281
OS Info
OS Name
Enhanced Magnets system
[1]
Photoreceptor (PR) Name
Negative Magnet (nMag)
PR Info
Components
Photoreceptor
Negative Magnet (nMag)
Complementary Protein
Positive Magnet (pMag)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00280
OS Info
OS Name
Optogenetic regulate Galpha activity system 2
[2]
Photoreceptor (PR) Name
Negative Magnet (nMag)
PR Info
Components
Photoreceptor
Negative Magnet (nMag)
Complementary Protein
Positive Magnet (pMag)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00346
OS Info
OS Name
Optogenetic regulate Galpha activity system 3
[2]
Photoreceptor (PR) Name
Negative Magnet (nMag (C71S))
PR Info
Components
Photoreceptor
Negative Magnet (nMag (C71S))
Complementary Protein
Positive Magnet (pMag)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00699
OS Info
OS Name
Photoactivatable targeted gene editing system
[3]
Photoreceptor (PR) Name
Negative Magnet (nMag)
PR Info
Components
Photoreceptor
Negative Magnet (nMag)
Complementary Protein
Positive Magnet (pMag)
Cofactor
Flavin adenine dinucleotide (FAD)
References
1 Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells
2 Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems
3 Split-Cas9-based targeted gene editing and nanobody-mediated proteolysis-targeting chimeras optogenetically coordinated regulation of Survivin to control the fate of cancer cells