General Information of This Photoreceptor (PR)
PR ID PR00159
PR Name Negative Magnet (nMag (C71S))
Source of Species Neurospora crassa
Class LOV domain
Mutation Site C71S
Sequence
HTLYAPGGYDIMGYLDQIGNRPNPQVELGPVDTSCALILCDLKKDTPIVYASEAFLYMTC
RSNAEVLGRNSRFLQSPDGMVKPKSTRKYVDSNTINTMRKAIDRNAEVQVEVVNFKKNGQ
RFVNFLTMIPVRDETGEYRYSMGFQCETE
Components Photoreceptor Negative Magnet (nMag (C71S))
Complementary Protein Positive Magnet (pMag)
Detail Info
Cofactor Flavin adenine dinucleotide (FAD)
Detail Info
3D Structure
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Complementary Protein Detail of This PR
Complementary Protein Positive Magnet (pMag)
Sequence
HTLYAPGGYDIMGYLRQIRNRPNPQVELGPVDTSCALILCDLKQKDTPIVYASEAFLYMT
GYSNAEVLGRNCRFLQSPDGMVKPKSTRKYVDSNTINTMRKAIDRNAEVQVEVVNFKKNG
QRFVNFLTMIPVRDETGEYRYSMGFQCETE
Cofactor Detail of This PR
Cofactor Name Flavin adenine dinucleotide (FAD)
PubChem CID 643975
Structure
Formula C27H33N9O15P2
Molecular Weight 785.5
Optogenetic System (OS) Consisting of This PR
OS00346
OS Info
OS Name: Optogenetic regulate Galpha activity system 3 (Opto-Galpha 3)
[1]
Recruited protein: Guanine nucleotide-binding protein G(q) subunit alpha
Functional protein: Negative Magnet
References
1 Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems