General Information of This Photoreceptor (PR)
PR ID PR00322
PR Name Aureochromes 1 from Vaucheria frigida (AuLOV)
Source of Species Vaucheria frigida
Class LOV domain
UniProt ID A8QW55
GenBank BAF91488.1
PDB ID 3UE6
Sequence
MNGLTPPLMFCSRSDDPSSTSNINLDDVFADVFFNSNGELLDIDEIDDFGDNTCPKSSMS
VDDDASSQVFQGHLFGNALSSIALSDSGDLSTGIYESQGNASRGKSLRTKSSGSISSELT
EAQKVERRERNREHAKRSRVRKKFLLESLQQSVNELNHENNCLKESIREHLGPRGDSLIA
QCSPEADTLLTDNPSKANRILEDPDYSLVKALQMAQQNFVITDASLPDNPIVYASRGFLT
LTGYSLDQILGRNCRFLQGPETDPRAVDKIRNAITKGVDTSVCLLNYRQDGTTFWNLFFV
AGLRDSKGNIVNYVGVQSKVSEDYAKLLVNEQNIEYKGVRTSNMLRRK
Components Photoreceptor Aureochromes 1 from Vaucheria frigida (AuLOV)
Cofactor Flavin mononucleotide (FMN)
Detail Info
3D Structure
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Cofactor Detail of This PR
Cofactor Name Flavin mononucleotide (FMN)
PubChem CID 643976
Structure
Formula C17H21N4O9P
Molecular Weight 456.3
Optogenetic System (OS) Consisting of This PR
OS00727
OS Info
OS Name: opto-TLR4 ECD2-LOV LECs (opto-TLR4 ECD2-LOV LECs)
[1]
Fusion protein: Toll-like receptor 4
OS00726
OS Info
OS Name: opto-TLR4-LOV HUVECs (opto-TLR4-LOV HUVECs)
[1]
Fusion protein: Toll-like receptor 4
OS00725
OS Info
OS Name: opto-TLR4-LOV LECs (opto-TLR4-LOV LECs)
[1]
Fusion protein: Toll-like receptor 4
OS00563
OS Info
OS Name: Optogenetic controlled iTrkB signaling system 4 (Opto-iTrkB 4)
[2]
Fusion protein: Intracellular Tropomyosin receptor kinase B
OS00564
OS Info
OS Name: Optogenetic controlled iTrkB signaling system 5 (Opto-iTrkB 5)
[2]
Fusion protein: Intracellular Tropomyosin receptor kinase B
OS00619
OS Info
OS Name: Optogenetic regulate Toll-like Receptor 4 system (Opto-TLR4)
[3]
Fusion protein: Toll-like receptor 4
OS00620
OS Info
OS Name: Optogenetic regulate Voltage-gated potassium channel system (Opto-Kv1)
[4]
Fusion protein: Potassium channel
References
1 Comparative and Temporal Characterization of LPS and Blue-Light-Induced TLR4 Signal Transduction and Gene Expression in Optogenetically Manipulated Endothelial Cells
2 Optical Activation of TrkB Signaling
3 Light-Inducible Spatio-Temporal Control of TLR4 and NF-B-Gluc Reporter in Human Pancreatic Cell Line
4 Light-regulated voltage-gated potassium channels for acute interrogation of channel function in neurons and behavior