Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00357
CP Name C terminal of GTPase HRas (HRasCT)
CP Type Fusion protein
Common Name GTPase HRas (EC 3.6.5.2) (H-Ras-1) (Ha-Ras) (Transforming protein p21) (c-H-ras) (p21ras) [Cleaved into: GTPase HRas, N-terminally processed]
Organism Homo sapiens (Human)
UniProt ID P01112
UniProt Entry RASH_HUMAN
KEGG hsa:3265
Function Involved in the activation of Ras protein signal transduction. Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.
Sequence
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDL
AARTVESRQAQDLARSYGIPYIETSAKTRQGVEDAFYTLVREIRQHKLRKLNPPDESGPC
MSCKCVLS
Optogenetic System (OS) Controlling This CP
OS00596
OS Info
OS Name
Light-induced dimerization system 1
[1], [2]
Photoreceptor (PR) Name
Residue1-908 of Phytochrome B (PhyB (1-908))
PR Info
Components
Photoreceptor
Residue1-908 of Phytochrome B (PhyB (1-908))
Complementary Protein
Phytochrome interacting factor 6; PIF6 (PIF6)
Cofactor
Phycocyanobilin (PCB)
OS00532
OS Info
OS Name
Light-induced dimerization system 2
[1], [2]
Photoreceptor (PR) Name
Residue1-621 of Phytochrome B (PhyB (1-621))
PR Info
Components
Photoreceptor
Residue1-621 of Phytochrome B (PhyB (1-621))
Complementary Protein
Phytochrome interacting factor 3 (PIF3)
Cofactor
Phycocyanobilin (PCB)
References
1 Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling
2 Improvement of Phycocyanobilin Synthesis for Genetically Encoded Phytochrome-Based Optogenetics