General Information of This Photoreceptor (PR)
PR ID PR00118
PR Name LOV2 Trapping of Protein (LOVTRAP)
Source of Species Avena sativa
Class LOV domain
UniProt ID O49003
GenBank 1047463129
PDB ID 5EFW
Sequence
LATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATV
RKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDA
AEREGVMLIKKTAENIDEAAKEL
Components Photoreceptor LOV2 Trapping of Protein (LOVTRAP)
Complementary Protein Zdark (ZDK)
Detail Info
Cofactor Flavin mononucleotide (FMN)
Detail Info
3D Structure
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Complementary Protein Detail of This PR
Complementary Protein Zdark (ZDK)
Sequence
GSVDNKFNKEKTRAGAEIHSLPNLNVEQKFAFIVSLFDDPSQSANLLAEAKKLNDAQAPK
Cofactor Detail of This PR
Cofactor Name Flavin mononucleotide (FMN)
PubChem CID 643976
Structure
Formula C17H21N4O9P
Molecular Weight 456.3
Optogenetic System (OS) Consisting of This PR
OS00228
OS Info
OS Name: LOV2 trap and release of protein system (LOVTRAP)
[1]
Functional protein: LOV2 domain of Avena sativa Phototropin 1
Recruited protein: Zdark
OS00232
OS Info
OS Name: Optogenetic control alphaTAT activity by LOVTRAP system 1 (OptoalphaTAT-LOVTRAP 1)
[2] , [3]
Fusion protein: Alpha-tubulin acetyl transferase
OS00231
OS Info
OS Name: Optogenetic control coffilin activity by LOVTRAP system 1 (OptoCOF-LOVTRAP 1)
[2] , [3]
Fusion protein: Cofilin; a actin-binding protein
OS00229
OS Info
OS Name: Versatile method to control protein function by LOVTRAP system 1-1 (LOVTRAP 1-1)
[4]
Functional protein: LOV2 domain of Avena sativa Phototropin 1
Recruited protein: Zdark
OS00230
OS Info
OS Name: Versatile method to control protein function by LOVTRAP system 1-2 (LOVTRAP 1-2)
[4]
Functional protein: LOV2 domain of Avena sativa Phototropin 1
Recruited protein: Zdark
References
1 Using Tools from Optogenetics to Create Light-Responsive Biomaterials: LOVTRAP-PEG Hydrogels for Dynamic Peptide Immobilization
2 Optogenetic control of cofilin and TAT in living cells using Z-lock
3 Engineering Optogenetic Protein Analogs
4 LOVTRAP: A Versatile Method to Control Protein Function with Light