General Information of This Controlled Protein (CP)
CP ID CP00549
CP Name NTF2-related export protein 1 (Nxt1 (P15))
CP Type Fusion protein
Common Name NTF2-related export protein 1
Organism Homo sapiens (Human)
UniProt ID Q9UKK6
UniProt Entry NXT1_HUMAN
KEGG hsa:29107
Function Stimulator of protein export for NES-containing proteins. Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA. The NXF1-NXT1 heterodimer is involved in the export of HSP70 mRNA in conjunction with ALYREF/THOC4 and THOC5.
Sequence
MASVDFKTYVDQACRAAEEFVNVYYTTMDKRRRLLSRLYMGTATLVWNGNAVSGQESLSE
FFEMLPSSEFQISVVDCQPVHDEATPSQTTVLVVICGSVKFEGNKQRDFNQNFILTAQAS
PSNTVWKIASDCFRFQDWAS
Optogenetic System (OS) Controlling This CP
OS00719
OS Info
OS Name
Bue light-inducible nuclear export system - i 3
[1]
Photoreceptor (PR) Name
LOV2 domain of Avena sativa Phototropin 1 (V416I) (AsLOV2 (V416I))
PR Info
Components
Photoreceptor
LOV2 domain of Avena sativa Phototropin 1 (V416I) (AsLOV2 (V416I))
Cofactor
Flavin mononucleotide (FMN)
OS00723
OS Info
OS Name
Bue light-inducible nuclear export system - s 3
[1]
Photoreceptor (PR) Name
LOV2 domain of Avena sativa Phototropin 1 (V416L) (AsLOV2 (V416L))
PR Info
Components
Photoreceptor
LOV2 domain of Avena sativa Phototropin 1 (V416L) (AsLOV2 (V416L))
Cofactor
Flavin mononucleotide (FMN)
OS00715
OS Info
OS Name
Bue light-inducible nuclear export system 3
[1]
Photoreceptor (PR) Name
LOV2 domain of Avena sativa Phototropin 1 (AsLOV2)
PR Info
Components
Photoreceptor
LOV2 domain of Avena sativa Phototropin 1 (AsLOV2)
Cofactor
Flavin mononucleotide (FMN)
References
1 Analysis of Slow-Cycling Variants of the Light-Inducible Nuclear Protein Export System LEXY in Mammalian Cells