Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00311
CP Name Costmulatory domain of Tumor necrosis factor receptor superfamily member 9 (4-1BB)
CP Type Fusion protein
Common Name Tumor necrosis factor receptor superfamily member 9 (4-1BB ligand receptor) (CDw137) (T-cell antigen 4-1BB homolog) (T-cell antigen ILA) (CD antigen CD137)
Organism Homo sapiens (Human)
UniProt ID Q07011
UniProt Entry TNR9_HUMAN
KEGG hsa:3604
Function Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.
Sequence
RTRSLQDPCSNCPAGTFCDNNRNQICSPCPPNSFSSAGGQRTCDICRQCKGVFRTRKECS
STSNAECDCTPGFHCLGAGCSMCEQDCKQGQELTKKGCKDCCFGTFNDQKRGICRPWTNC
SLDGKSVLVNGTKERDVVCGPSPADLSPGASSVTPPAPARE
Optogenetic System (OS) Controlling This CP
OS00201
OS Info
OS Name
Optogenetic controlled CAR-T cell signal system
[1]
Photoreceptor (PR) Name
LOV2 domain of circular permutants (cpLOV2)
PR Info
Components
Photoreceptor
LOV2 domain of circular permutants (cpLOV2)
Complementary Protein
Engineered protein Zdk2 affibody (Zdk2)
Cofactor
Flavin mononucleotide (FMN)
References
1 Circularly permuted LOV2 as a modular photoswitch for optogenetic engineering