General Information of This Controlled Protein (CP)
CP ID CP00241
CP Name Phytochrome B (PhyB)
CP Type Functional protein
Common Name Phytochrome B (Protein LONG HYPOCOTYL 3) (Protein OUT OF PHASE 1)
Organism Arabidopsis thaliana (Mouse-ear cress)
UniProt ID P14713
UniProt Entry PHYB_ARATH
KEGG ath:AT2G18790
Function Regulatory photoreceptor which exists in two forms that are reversibly interconvertible by light: the Pr form that absorbs maximally in the red region of the spectrum and the Pfr form that absorbs maximally in the far-red region. Photoconversion of Pr to Pfr induces an array of morphogenetic responses, whereas reconversion of Pfr to Pr cancels the induction of those responses. Pfr controls the expression of a number of nuclear genes including those encoding the small subunit of ribulose-bisphosphate carboxylase, chlorophyll A/B binding protein, protochlorophyllide reductase, rRNA, etc. It also controls the expression of its own gene(s) in a negative feedback fashion. Involved in the flowering time regulation. Involved in light-regulated circadian phase control that triggers stomatal aperture, stomatal conductance, and CO(2) assimilation. Implicated in red light perception, and, to a lower extent, in blue light signaling. Regulates temperature responses by associating with the promoters of key target genes in a temperature-dependent manner and subsequently repressing their expression probably in a PIF4-dependent manner. Thermal timer that integrates temperature information over the course of the night.
Sequence
MVSGVGGSGGGRGGGRGGEEEPSSSHTPNNRRGGEQAQSSGTKSLRPRSNTESMSKAIQQ
YTVDARLHAVFEQSGESGKSFDYSQSLKTTTYGSSVPEQQITAYLSRIQRGGYIQPFGCM
IAVDESSFRIIGYSENAREMLGIMPQSVPTLEKPEILAMGTDVRSLFTSSSSILLERAFV
AREITLLNPVWIHSKNTGKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVR
AISQLQALPGGDIKLLCDTVVESVRDLTGYDRVMVYKFHEDEHGEVVAESKRDDLEPYIG
LHYPATDIPQASRFLFKQNRVRMIVDCNATPVLVVQDDRLTQSMCLVGSTLRAPHGCHSQ
YMANMGSIASLAMAVIINGNEDDGSNVASGRSSMRLWGLVVCHHTSSRCIPFPLRYACEF
LMQAFGLQLNMELQLALQMSEKRVLRTQTLLCDMLLRDSPAGIVTQSPSIMDLVKCDGAA
FLYHGKYYPLGVAPSEVQIKDVVEWLLANHADSTGLSTDSLGDAGYPGAAALGDAVCGMA
VAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFQAFLEVVKSRSQPWE
TAEMDAIHSLQLILRDSFKES
Optogenetic System (OS) Controlling This CP
OS00543
OS Info
OS Name
Optogenetic regulate ligand -T-cell receptor interaction system
[1], [2], [3]
Photoreceptor (PR) Name
Phytochrome B tetramer (PhyBt)
PR Info
Components
Photoreceptor
Phytochrome B tetramer (PhyBt)
Complementary Protein
Phytochrome interacting factor 6 (C9S/C10S/S37A) (PIFS=PIF6(C9S/C10S/S37A))
Cofactor
Phycocyanobilin (PCB)
References
1 Optogenetic control shows that kinetic proofreading regulates the activity of the T cell receptor
2 Optogenetic Tuning of Ligand Binding to The Human T cell Receptor Using The opto-ligand-TCR System
3 Cross-TCR Antagonism Revealed by Optogenetically Tuning the Half-Life of the TCR Ligand Binding