General Information of This Photoreceptor (PR)
PR ID PR00083
PR Name LOV2 domain of Avena sativa Phototropin 1 (C450A) (AsLOV2 (C450A))
Source of Species Avena sativa
Class LOV domain
UniProt ID O49003
GenBank 162330142
PDB ID 2V1A
Mutation Site C450A
Sequence
LATTLERIEKNFVITDPRLPDNPIIFASDSFLQLTEYSREEILGRNARFLQGPETDRATV
RKIRDAIDNQTEVTVQLINYTKSGKKFWNLFHLQPMRDQKGDVQYFIGVQLDGTEHVRDA
AEREGVMLIKKTAENIDEAAKEL
Components Photoreceptor LOV2 domain of Avena sativa Phototropin 1 (C450A) (AsLOV2 (C450A))
Cofactor Flavin mononucleotide (FMN)
Detail Info
3D Structure
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Cofactor Detail of This PR
Cofactor Name Flavin mononucleotide (FMN)
PubChem CID 643976
Structure
Formula C17H21N4O9P
Molecular Weight 456.3
Optogenetic System (OS) Consisting of This PR
OS00174
OS Info
OS Name: Optogenetic JNK inhibit system 2 (OptoJNKi 2)
[1]
Fusion protein: Minimal JNK-binding protein 1
OS00173
OS Info
OS Name: Photo-activable Rac1 system 1 (PA-Rac1-1)
[2]
Fusion protein: Ras-related C3 botulinum substrate1
References
1 A simple optogenetic MAPK inhibitor design reveals resonance between transcription-regulating circuitry and temporally-encoded inputs
2 A genetically encoded photoactivatable Rac controls the motility of living cells