Details of the Optogenetic System
General Information of This Optogenetic System (OS) | ||||||
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OS ID |
OS00299
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OS Name |
Optogenetic regulate postsynaptic potentials in the pharyngeal system
(Opto-postP)
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[1] | ||||
Photoreceptor (PR) |
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Cofactor | All-trans-Retinal (Trans-Retinal) | |||||
Controlled Protein | Functional protein | Channelrhodopsin 2 | ||||
OS Application Information (1) | ||||||
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Mechanism of Action | Ion channel open | [ 1] | ||||
Controlled Signal Pathway | Neuron activation | |||||
Effect | Activation | |||||
Application | Optogenetic control muscle action potentials in the pharyngeal system | |||||
Note | Blocked by cholinergic receptor | |||||
Current Intensity | 71 mV | |||||
Channel Type | Cation channel | |||||
Light Information | Activation Wavelength | 479 nm | ||||
Process | Reversible | |||||
Deactivation Wavelength | Dark | |||||
Activation Time | 0.2 ms | |||||
Light Intensity | 0.5 milliwatts per square miliimeter | |||||
Expression Information | Expression Method | Transformation | ||||
Cell Lines | Caenorhabditis elegans cholinergic neurons in the pharyngeal system | |||||