Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00475
CP Name Opto-a1AR (Opto-a1AR)
CP Type Functional protein
Sequence
MNGTEGPNFYVPFSNKTGVVRSPFEAPQYYLAEPWQFSMLAAYMFLLIMLGFPINFLTLY
VVACHRHLHSVLNYILLNLAVADLFMVFGGFTTTLYTSLHGYFVFGPTGCNLEGFFATLG
GEIALWSLVVLAIERYVVVSYPLRYPTIVTQRRAIMGVAFTWVMALACAAPPLVGWSRYI
PEGMQCSCGIDYYTPHEETNNESFVIYMFVVHFIIPLIVIFFCYGRVYVVAKRESRGLKS
GLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAARMVIIMVIA
FLICWLPYAGVAFYIFTHQGSDFGPIFMTIPAFFAKTSAVYNPVIYIMMNKQFRKAFQNV
LRIQCLCRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYRISKTDGVCEWKFF
SSMPRGSARITVSKDQSSCTTARVRSKSFLQVCCCVGPSTPSLDKNHQVPTIKVHTISLS
ENGEEVTETSQVAPA
Optogenetic System (OS) Controlling This CP
OS00008
OS Info
OS Name
Cofilin-actin interaction optocontroled regulated system
[1]
Photoreceptor (PR) Name
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
PR Info
Components
Photoreceptor
Photolyase homology region of Arabidopsis Cryptochromes 2 (CRY2PHR)
Complementary Protein
Cryptochrome-interacting basic-helix-loop-helix 1 (CIB1/CIBN)
Cofactor
Flavin adenine dinucleotide (FAD)
OS00704
OS Info
OS Name
Opto-Gq-type GPCR Opto1AR
[2], [3]
Photoreceptor (PR) Name
Opto-1AR (Opto-1AR)
PR Info
Components
Photoreceptor
Opto-1AR (Opto-1AR)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00606
OS Info
OS Name
Optogenetic regulate hippocampal astrocytes system
[4], [5]
Photoreceptor (PR) Name
Opto-1AR (Opto-1AR)
PR Info
Components
Photoreceptor
Opto-1AR (Opto-1AR)
Cofactor
All-trans-Retinal (Trans-Retinal)
References
1 CofActor: A light- and stress-gated optogenetic clustering tool to study disease-associated cytoskeletal dynamics in living cells
2 Astrocytic GPCR-Induced Ca2+Signaling Is Not Causally Related to Local Cerebral Blood Flow Changes
3 Transient Astrocytic Gq Signaling Underlies Remote Memory Enhancement
4 Optogenetic Activation of Astrocytes-Effects on Neuronal Network Function
5 Temporally precise in vivo control of intracellular signalling