General Information of This Controlled Protein (CP)
CP ID CP00434
CP Name Secreted alkaline phosphatase (SEAP)
CP Type Recruited protein
Common Name Alkaline phosphatase, placental type (EC 3.1.3.1) (Alkaline phosphatase Regan isozyme) (Placental alkaline phosphatase 1) (PLAP-1)
Organism Homo sapiens (Human)
UniProt ID P05187
UniProt Entry PPB1_HUMAN
KEGG hsa:250
Function Alkaline phosphatase that can hydrolyze various phosphate compounds.
Sequence
MLGPCMLLLLLLLGLRLQLSLGIIPVEEENPDFWNREAAEALGAAKKLQPAQTAAKNLII
FLGDGMGVSTVTAARILKGQKKDKLGPEIPLAMDRFPYVALSKTYNVDKHVPDSGATATA
YLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAG
TYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFRMGTPDPEYP
DDYSQGGTRLDGKNLVQEWLAKRQGARYVWNRTELMQASLDPSVTHLMGLFEPGDMKYEI
HRDSTLDPSLMEMTEAALRLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAI
ERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPG
YVLKDGARPDVTESESGSPEYRQQSAVPLDEETHAGEDVAVFARGPQAHLVHGVQEQTFI
AHVMAFAACLEPYTACDLAPPAGTTDAAHPGRSVVPALLPLLAGTLLLLETATAP
Optogenetic System (OS) Controlling This CP
OS00525
OS Info
OS Name
Optogenetic control secreted alkaline phosphatase expression system
[1]
Photoreceptor (PR) Name
Phytochrome B (PhyB)
PR Info
Components
Photoreceptor
Phytochrome B (PhyB)
Complementary Protein
Phytochrome interacting factor 6 (PIF6)
Cofactor
Phycocyanobilin (PCB)
References
1 Deconstructing and repurposing the light-regulated interplay between Arabidopsis phytochromes and interacting factors