Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00381
CP Name KRAB domain of a transrepressor domain (KRAB)
CP Type Fusion protein
Common Name Zinc finger protein 10 (Zinc finger protein KOX1)
Organism Homo sapiens (Human)
UniProt ID P21506
UniProt Entry ZNF10_HUMAN
KEGG hsa:7556
Function May be involved in transcriptional regulation.
Sequence
VTFKDVFVDFTREEWKLLDTAQQIVYRNVMLENYKNLVSLGYQLTKPDVILRLEKGEEPW
LVEREIHQETHP
Optogenetic System (OS) Controlling This CP
OS00256
OS Info
OS Name
Blue liight-responsive optogenetic OFF switch
[1], [2]
Photoreceptor (PR) Name
Erythrobacter litoralis 222 amino acid protein (EL222)
PR Info
Components
Photoreceptor
Erythrobacter litoralis 222 amino acid protein (EL222)
Cofactor
Flavin mononucleotide (FMN)
References
1 Dual-controlled optogenetic system for the rapid down-regulation of protein levels in mammalian cells
2 Silencing of RNA polymerases II and III-dependent transcription by the KRAB protein domain of KOX1, a Krppel-type zinc finger factor