Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00104
CP Name Volvox channelrhodopsin-1 (VChR1)
CP Type Functional protein
Common Name Channelrhodopsin-1
Organism Volvox carteri f. nagariensis
UniProt ID B4Y103
UniProt Entry B4Y103_VOLCA
Sequence
MDYGGALSAVGRELLFVTNPVVVNGSVLVPEDQCYCAGWIESRGTNGAQTASNVLQWLAA
GFSILLLMFYAYQTWKSTCGWEEIYVCAIEMVKVILEFFFEFKNPSMLYLATGHRVQWLR
YAEWLLTCPVILIHLSNLTGLSNDYSRRTMGLLVSDIGTIVWGATSAMATGYVKVIFFCL
GLCYGANTFFHAAKAYIEGYHTVPKGRCRQVVTGMAWLFFVSWGMFPILFILGPEGFGVL
SVYGSTVGHTIIDLMSKNCWGLLGHYLRVLIHEHILIHGDIRKTTKLNIGGTEIEVETLV
EDEAEAGAVNKGTGK
Optogenetic System (OS) Controlling This CP
OS00307
OS Info
OS Name
Enhenced iteration of the excitory liminopsin LMO3
[1]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00312
OS Info
OS Name
Luminopsin 3 induced pluripotent stem cell-derived neural progenitor cells system
[2]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00306
OS Info
OS Name
Luminopsin 3 system
[3], [], []
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00311
OS Info
OS Name
Optogenetic activate neuron by LMO 3 system
[4]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00305
OS Info
OS Name
Optogenetic control opsin activity by luciferase 1
[5]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00308
OS Info
OS Name
Optogenetic fast neural control system
[6]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00309
OS Info
OS Name
Optogenetic investigate the cellular E/I balance hypothesis in freely moving mammals
[7]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
OS00310
OS Info
OS Name
Optogenetic visual restoration system 1
[8]
Photoreceptor (PR) Name
Volvox channelrhodopsin 1 (VChR1)
PR Info
Components
Photoreceptor
Volvox channelrhodopsin 1 (VChR1)
Cofactor
All-trans-Retinal (Trans-Retinal)
References
1 Improved trafficking and expression of luminopsins for more efficient optical and pharmacological control of neuronal activity
2 Optochemogenetic Stimulation of Transplanted iPS-NPCs Enhances Neuronal Repair and Functional Recovery after Ischemic Stroke
3 Bioluminescence-driven optogenetic activation of transplanted neural precursor cells improves motor deficits in a Parkinson's disease mouse model
4 Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation
5 Novel luciferase-opsin combinations for improved luminopsins
6 Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri
7 Neocortical excitation/inhibition balance in information processing and social dysfunction
8 Restoration of the majority of the visual spectrum by using modified Volvox channelrhodopsin-1