Details of the Optogenetic Tool

General Information of This Photoreceptor (PR)
PR ID PR00392
PR Name BcWCL1PAS (BcWCL1PAS)
Source of Species Botryotinia fuckeliana (strain B05.10) (Noble rot fungus) (Botrytis cinerea)
Class LOV domain
UniProt ID A0A384JAY1
Sequence
MSNFFNMPMTQADLQRQVAQRRAHSRSLSIPQPQPQQQQRQQQQPSTQSNGNSMNMNHNM
SGGNSLDEIIMQNNNELQRRQSYSQDFSQDHDRRSSMLEFGNSDVGLNDFQFGTPTPSSE
NPMIRRQSLGEMNMNDLYGGGMDSGMGIMPQMQQLGYSDSVRPNLMDTTMGYGSYSGDMM
PGMMSYASIGMDGMSQDSPMGMYSNDNYSPTVYGNDPMDSMDSNMFMGGQDRGGIRTLGD
ENNEEMSSRSSIMGPTAAESLLRTREGMIMRPLEDENNEAMSSRFDVMGQSPSAMSMPQT
LINYNSPSASNAPPNLLTRTSSAAMIPTSVSTPTALAVNVVFRIRRKNSGYTWFESHGSL
CAEQGKGRKCIVMVGRVRPVYALARSDLMRMDGLSDQQMYSKLSTSGMFLYVATNVRSLL
DRTPDDLVGTSIQALMRADSKVAFGRALEKARTGKIVKYSHELFNKRGLVIQTETVLYPG
DASEGHKPTFLVAQTRLVNKASRNVASATGANGTNIPGGKAMIMSPMIRTDTQTSDGMSS
NNQSVRPQASPFPEPMTPGVSGTATVPITQPGGSGLPIGSQDEALASRDNIFEELKTTRA
TSWQYELRQMEKENRSLAEEVASLVNARKKRKRRKLPGNVQRDCANCHTKNTPEWRRGPS
GNRDLCNSCGLRWAKQQGRISSRSSKRSKDGDASSKHSNSPSHSSPLHNEISQNSESLNP
NLNINPGKPADSTVPRPAKLLKKESDGSVRTASTGSPVTSVEGTGKTGQSKIGQGNIGPG
GISNGGVMGSGTAVPASLGGRTTMESQPFHARSLGFNEGGVSGITNIAEGGESERSGKTS
GMN
Components Photoreceptor BcWCL1PAS (BcWCL1PAS)
Cofactor Flavin adenine dinucleotide (FAD)
Detail Info
3D Structure
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Cofactor Detail of This PR
Cofactor Name Flavin adenine dinucleotide (FAD)
PubChem CID 643975
Structure
Formula C27H33N9O15P2
Molecular Weight 785.5
Optogenetic System (OS) Consisting of This PR
OS00728
OS Info
OS Name: Optogenetics system activates by BcWCL1PAS 1 (Opto-BcWCL1PAS 1)
[1] , [2]
Fusion protein: DNA Binding Domain
Detail Info
OS00729
OS Info
OS Name: Optogenetics system activates by BcWCL1PAS 2 (Opto-BcWCL1PAS 2)
[1] , [2]
Fusion protein: Activation domain
Detail Info
References
1 The N-Terminal Region of the BcWCL1 Photoreceptor Is Necessary for Self-Dimerization and Transcriptional Activation upon Light Stimulation in Yeast
2 Interactions between Core Elements of theBotrytis cinereaCircadian Clock Are Modulated by Light and Different Protein Domains