Details of the Optogenetic Tool

General Information of This Photoreceptor (PR)
PR ID PR00303
PR Name Phytochrome B (PhyB)
Source of Species Arabidopsis
Class Phytochromes
UniProt ID P14713
GenBank NP_179469
PDB ID 4OUR
Sequence
MVSGVGGSGGGRGGGRGGEEEPSSSHTPNNRRGGEQAQSSGTKSLRPRSNTESMSKAIQQ
YTVDARLHAVFEQSGESGKSFDYSQSLKTTTYGSSVPEQQITAYLSRIQRGGYIQPFGCM
IAVDESSFRIIGYSENAREMLGIMPQSVPTLEKPEILAMGTDVRSLFTSSSSILLERAFV
AREITLLNPVWIHSKNTGKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVR
AISQLQALPGGDIKLLCDTVVESVRDLTGYDRVMVYKFHEDEHGEVVAESKRDDLEPYIG
LHYPATDIPQASRFLFKQNRVRMIVDCNATPVLVVQDDRLTQSMCLVGSTLRAPHGCHSQ
YMANMGSIASLAMAVIINGNEDDGSNVASGRSSMRLWGLVVCHHTSSRCIPFPLRYACEF
LMQAFGLQLNMELQLALQMSEKRVLRTQTLLCDMLLRDSPAGIVTQSPSIMDLVKCDGAA
FLYHGKYYPLGVAPSEVQIKDVVEWLLANHADSTGLSTDSLGDAGYPGAAALGDAVCGMA
VAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFQAFLEVVKSRSQPWE
TAEMDAIHSLQLILRDSFKESEAAMNSKVVDGVVQPCRDMAGEQGIDELGAVAREMVRLI
ETATVPIFAVDAGGCINGWNAKIAELTGLSVEEAMGKSLVSDLIYKENEATVNKLLSRAL
RGDEEKNVEVKLKTFSPELQGKAVFVVVNACSSKDYLNNIVGVCFVGQDVTSQKIVMDKF
INIQGDYKAIVHSPNPLIPPIFAADENTCCLEWNMAMEKLTGWSRSEVIGKMIVGEVFGS
CCMLKGPDALTKFMIVLHNAIGGQDTDKFPFPFFDRNGKFVQALLTANKRVSLEGKVIGA
FCFLQIPSPELQQALAVQRRQDTECFTKAKELAYICQVIKNPLSGMRFANSLLEATDLNE
DQKQLLETSVSCEKQISRIVGDMDLESIEDGSFVLKREEFFLGSVINAIVSQAMFLLRDR
GLQLIRDIPEEIKSIEVFGDQIRIQQLLAEFLLSIIRYAPSQEWVEIHLSQLSKQMADGF
AAIRTEFRMACPGEGLPPELVRDMFHSSRWTSPEGLGLSVCRKILKLMNGEVQYIRESER
SYFLIILELPVPRKRPLSTASGSGDMMLMMPY
Components Photoreceptor Phytochrome B (PhyB)
Complementary Protein Phytochrome interacting factor 6 (PIF6)
Detail Info
Cofactor Phycocyanobilin (PCB)
Detail Info
Complementary Protein Detail of This PR
Complementary Protein Phytochrome interacting factor 6 (PIF6)
UniProt ID Q8L5W7
Sequence
MMFLPTDYCCRLSDQEYMELVFENGQILAKGQRSNVSLHNQRTKSIMDLYEAEYNEDFMK
SIIHGGGGAITNLGDTQVVPQSHVAAAHETNMLESNKHVDDSETLKASSSKRMMVDYHNR
KKIKFIPPDEQSVVADRSFKLGFDTSSVGFTEDSEGSMYLSSSLDDESDDARPQVPARTR
KALVKRKRNAEAYNSPERNQRNDINKKMRTLQNLLPNSHKDDNESMLDEAINYMTNLQLQ
VQMMTMGNRFVTPSMMMPLGPNYSQMGLAMGVGMQMGEQQFLPAHVLGAGLPGINDSADM
LRFLNHPGLMPMQNSAPFIPTENCSPQSVPPSCAAFPNQIPNPNSLSNLDGATLHKKSRK
TNR
Cofactor Detail of This PR
Cofactor Name Phycocyanobilin (PCB)
PubChem CID 5280816
Structure
Formula C33H38N4O6
Molecular Weight 586.7
Optogenetic System (OS) Consisting of This PR
OS00527
OS Info
OS Name: Light-activated nuclear translocation of adeno-associated virus nanoparticles system 1 (LANT-AAV 1)
[1]
Recruited protein: Adeno-associated virus nanooparticles VNP-1,2
Detail Info
Functional protein: Phytochrome B
Detail Info
OS00528
OS Info
OS Name: Light-activated nuclear translocation of adeno-associated virus nanoparticles system 2 (LANT-AAV 2)
[1]
Recruited protein: Adeno-associated virus nanooparticles VNP-2
Detail Info
Functional protein: Phytochrome B
Detail Info
OS00525
OS Info
OS Name: Optogenetic control secreted alkaline phosphatase expression system (Opto-SEAP)
[2]
Recruited protein: Secreted alkaline phosphatase
Detail Info
Fusion protein: Virus protein 16
Detail Info
OS00526
OS Info
OS Name: Optogenetic control transcription activation system 1 (Opto-CTA 1)
[3]
Recruited protein: Phytochrome interacting factor 6
Detail Info
Fusion protein: Virus protein 16
Detail Info
OS00524
OS Info
OS Name: Red light control cell-cell interaction system (RLCC)
[4]
Recruited protein: Phytochrome interacting factor 6
Detail Info
Fusion protein: Platelet-derived growth factor receptor
Detail Info
References
1 Light-Activated Nuclear Translocation of Adeno-Associated Virus Nanoparticles Using Phytochrome B for Enhanced, Tunable, and Spatially Programmable Gene Delivery
2 Deconstructing and repurposing the light-regulated interplay between Arabidopsis phytochromes and interacting factors
3 Optogenetics in Plants: Red/Far-Red Light Control of Gene Expression
4 Independent Control over Multiple Cell Types in Space and Time Using Orthogonal Blue and Red Light Switchable Cell Interactions