Details of the Optogenetic Tool

General Information of This Photoreceptor (PR)
PR ID PR00302
PR Name Phytochrome B (PhyB)
Source of Species Arabidopsis
Class Phytochromes
UniProt ID P14713
GenBank NP_179469
PDB ID 4OUR
Sequence
MVSGVGGSGGGRGGGRGGEEEPSSSHTPNNRRGGEQAQSSGTKSLRPRSNTESMSKAIQQ
YTVDARLHAVFEQSGESGKSFDYSQSLKTTTYGSSVPEQQITAYLSRIQRGGYIQPFGCM
IAVDESSFRIIGYSENAREMLGIMPQSVPTLEKPEILAMGTDVRSLFTSSSSILLERAFV
AREITLLNPVWIHSKNTGKPFYAILHRIDVGVVIDLEPARTEDPALSIAGAVQSQKLAVR
AISQLQALPGGDIKLLCDTVVESVRDLTGYDRVMVYKFHEDEHGEVVAESKRDDLEPYIG
LHYPATDIPQASRFLFKQNRVRMIVDCNATPVLVVQDDRLTQSMCLVGSTLRAPHGCHSQ
YMANMGSIASLAMAVIINGNEDDGSNVASGRSSMRLWGLVVCHHTSSRCIPFPLRYACEF
LMQAFGLQLNMELQLALQMSEKRVLRTQTLLCDMLLRDSPAGIVTQSPSIMDLVKCDGAA
FLYHGKYYPLGVAPSEVQIKDVVEWLLANHADSTGLSTDSLGDAGYPGAAALGDAVCGMA
VAYITKRDFLFWFRSHTAKEIKWGGAKHHPEDKDDGQRMHPRSSFQAFLEVVKSRSQPWE
TAEMDAIHSLQLILRDSFKESEAAMNSKVVDGVVQPCRDMAGEQGIDELGAVAREMVRLI
ETATVPIFAVDAGGCINGWNAKIAELTGLSVEEAMGKSLVSDLIYKENEATVNKLLSRAL
RGDEEKNVEVKLKTFSPELQGKAVFVVVNACSSKDYLNNIVGVCFVGQDVTSQKIVMDKF
INIQGDYKAIVHSPNPLIPPIFAADENTCCLEWNMAMEKLTGWSRSEVIGKMIVGEVFGS
CCMLKGPDALTKFMIVLHNAIGGQDTDKFPFPFFDRNGKFVQALLTANKRVSLEGKVIGA
FCFLQIPSPELQQALAVQRRQDTECFTKAKELAYICQVIKNPLSGMRFANSLLEATDLNE
DQKQLLETSVSCEKQISRIVGDMDLESIEDGSFVLKREEFFLGSVINAIVSQAMFLLRDR
GLQLIRDIPEEIKSIEVFGDQIRIQQLLAEFLLSIIRYAPSQEWVEIHLSQLSKQMADGF
AAIRTEFRMACPGEGLPPELVRDMFHSSRWTSPEGLGLSVCRKILKLMNGEVQYIRESER
SYFLIILELPVPRKRPLSTASGSGDMMLMMPY
Components Photoreceptor Phytochrome B (PhyB)
Complementary Protein Phytochrome interacting factor 6 (C9S/C10S/S37A) (PIF6(C9S/C10S/S37A))
Detail Info
Cofactor Phycocyanobilin (PCB)
Detail Info
Complementary Protein Detail of This PR
Complementary Protein Phytochrome interacting factor 6 (C9S/C10S/S37A) (PIF6(C9S/C10S/S37A))
UniProt ID Q8L5W7
Sequence
MMFLPTDYSSRLSDQEYMELVFENGQILAKGQRSNVALHNQRTKSIMDLYEAEYNEDFMK
SIIHGGGGAITNLGDTQVVPQSHVAAAHETNMLESNKHVD
Cofactor Detail of This PR
Cofactor Name Phycocyanobilin (PCB)
PubChem CID 5280816
Structure
Formula C33H38N4O6
Molecular Weight 586.7
Optogenetic System (OS) Consisting of This PR
OS00523
OS Info
OS Name: Optogenetically regulate membrane receptor-ligand pair system (Opto-MCL)
[1]
Functional protein: Phytochrome B
Detail Info
Recruited protein: Phytochrome interacting factor 6
Detail Info
References
1 Optogenetic control of integrin-matrix interaction