Details of the Optogenetic System

General Information of This Optogenetic System (OS)
OS ID
OS00733
OS Name
Multicolor optogenetics 3 (Opto-Multicolor 3)
 [1]
Photoreceptor (PR)
PR Info
PR Name
ChrimsonR (ChrimsonR)
Source of Species
Synthetic construct
Class
Opsin
GenBank
AHH02126.1
Mutation Site
K176R
3D Structure
Components
Photoreceptor: ChrimsonR (ChrimsonR)
Cofactor: All-trans-Retinal (Trans-Retinal)
Cofactor All-trans-Retinal (Trans-Retinal)
Controlled Protein Functional protein ChrimsonR
Detail Info
OS Application Information (1)
Controlled Signal Pathway Synaptic pathway from the auditory cortex (AUD) to the posterior parietal cortex (PPC)
Effect Activation
Application Activate neuron
Note ChR2 (H134R), Chronos and ChrimsonR can achieve multiple-pathway manipulations
Light Information Activation Wavelength 405, 440 or 630 nm
Activation Time Microseconds
Light Intensity 8 - 13 miliwatt per square centimeter (630 nm)
Expression Information Expression Method Injection
Cell Lines Mice
References
1 Practical considerations in an era of multicolor optogenetics