Details of the Optogenetic System

General Information of This Optogenetic System (OS)
OS ID
OS00299
OS Name
Optogenetic regulate postsynaptic potentials in the pharyngeal system (Opto-postP)
 [1]
Photoreceptor (PR)
PR Info
PR Name
Channelrhodopsin 2 (ChR2)
Source of Species
Chlamydomonas reinhardtii
Class
Opsin
UniProt ID
Q8RUT8
GenBank
1304111922
PDB ID
6EID
3D Structure
Components
Photoreceptor: Channelrhodopsin 2 (ChR2)
Cofactor: All-trans-Retinal (Trans-Retinal)
Cofactor All-trans-Retinal (Trans-Retinal)
Controlled Protein Functional protein Channelrhodopsin 2
Detail Info
OS Application Information (1)
Mechanism of Action Ion channel open [ 1]
Controlled Signal Pathway Neuron activation
Effect Activation
Application Optogenetic control muscle action potentials in the pharyngeal system
Note Blocked by cholinergic receptor
Current Intensity 71 mV
Channel Type Cation channel
Light Information Activation Wavelength 479 nm
Process Reversible
Deactivation Wavelength Dark
Activation Time 0.2 ms
Light Intensity 0.5 milliwatts per square miliimeter
Expression Information Expression Method Transformation
Cell Lines Caenorhabditis elegans cholinergic neurons in the pharyngeal system
References
1 A comparison of electrically evoked and channel rhodopsin-evoked postsynaptic potentials in the pharyngeal system of Caenorhabditis elegans