Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00098
CP Name Channelrhodopsin 2 (ChR2)
CP Type Functional protein
Common Name Archaeal-type opsin 2 (Chlamyopsin 4 light-gated ion channel) (Retinal binding protein) (Sensory opsin B)
Organism Chlamydomonas reinhardtii (Chlamydomonas smithii)
UniProt ID Q8RUT8
UniProt Entry Q8RUT8_CHLRE
KEGG cre:CHLRE_02g085257v5
Sequence
MDYGGALSAVGRELLFVTNPVVVNGSVLVPEDQCYCAGWIESRGTNGAQTASNVLQWLAA
GFSILLLMFYAYQTWKSTCGWEEIYVCAIEMVKVILEFFFEFKNPSMLYLATGHRVQWLR
YAEWLLTSPVILIHLSNLTGLSNDYSRRTMGLLVSAIGCIVWGATSAMATGYVKVIFFCL
GLCYGANTFFHAAKAYIEGYHTVPKGRCRQVVTGMAWLFFVSWGMFPILFILGPEGFGVL
SVYGSTVGHTIIDLMSKNCWGLLGHYLRVLIHEHILIHGDIRKTTKLNIGGTEIEVETLV
EDEAEAGAVNKGTGK
Optogenetic System (OS) Controlling This CP
OS00282
OS Info
OS Name
Step-function opsin with ultra-high light sensitity
[1], [2]
Photoreceptor (PR) Name
Channelrhodopsin 2 (C128S; D156A; T159C) (ChR2 (C128S; D156A; T159C))
PR Info
Components
Photoreceptor
Channelrhodopsin 2 (C128S; D156A; T159C) (ChR2 (C128S; D156A; T159C))
Cofactor
All-trans-Retinal (Trans-Retinal)
References
1 An Ultra-Sensitive Step-Function Opsin for Minimally Invasive Optogenetic Stimulation in Mice and Macaques
2 Light takes a deep dive