General Information of This Photoreceptor (PR)
PR ID PR00368
PR Name Cryptochromes 2 (1-535; E490G) (CRY2olig (535))
Source of Species Arabidopsis thaliana
Class Cryptochromes
UniProt ID Q96524
GenBank NP_849588
PDB ID 6X24
Mutation Site E490G
Sequence
MKMDKKTIVWFRRDLRIEDNPALAAAAHEGSVFPVFIWCPEEEGQFYPGRASRWWMKQSL
AHLSQSLKALGSDLTLIKTHNTISAILDCIRVTGATKVVFNHLYDPVSLVRDHTVKEKLV
ERGISVQSYNGDLLYEPWEIYCEKGKPFTSFNSYWKKCLDMSIESVMLPPPWRLMPITAA
AEAIWACSIEELGLENEAEKPSNALLTRAWSPGWSNADKLLNEFIEKQLIDYAKNSKKVV
GNSTSLLSPYLHFGEISVRHVFQCARMKQIIWARDKNSEGEESADLFLRGIGLREYSRYI
CFNFPFTHEQSLLSHLRFFPWDADVDKFKAWRQGRTGYPLVDAGMRELWATGWMHNRIRV
IVSSFAVKFLLLPWKWGMKYFWDTLLDADLECDILGWQYISGSIPDGHELDRLDNPALQG
AKYDPEGEYIRQWLPELARLPTEWIHHPWDAPLTVLKASGVELGTNYAKPIVDIDTAREL
LAKAISRTRGAQIMIGAAPDEIVADSFEALGANTIKEPGLCPSVSSNDQQVPSAV
Components Photoreceptor Cryptochromes 2 (1-535; E490G) (CRY2olig (535))
Cofactor Flavin adenine dinucleotide (FAD)
Detail Info
3D Structure
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Cofactor Detail of This PR
Cofactor Name Flavin adenine dinucleotide (FAD)
PubChem CID 643975
Structure
Formula C27H33N9O15P2
Molecular Weight 785.5
Optogenetic System (OS) Consisting of This PR
OS00647
OS Info
OS Name: m-optoSynC, a tool foroptogeneticsynaptic vesicleclustering (m-optoSynC)
[1]
Functional protein: Arabidopsis thalianaCryptochrome-2 variants with C-terminal charge alteration (535)
OS00644
OS Info
OS Name: optoSynC, a tool foroptogeneticsynaptic vesicleclustering 1 (optoSynC 1)
[1]
Fusion protein: Synaptic vesicles protein synaptogyrin
OS00645
OS Info
OS Name: optoSynC, a tool foroptogeneticsynaptic vesicleclustering 2 (optoSynC 2)
[1]
Fusion protein: Synaptic vesicles protein synaptogyrin
OS00646
OS Info
OS Name: optoSynC, a tool foroptogeneticsynaptic vesicleclustering 3 (optoSynC 3)
[1]
Fusion protein: Synaptic vesicles protein synaptogyrin
References
1 Rapid and reversible optogenetic silencing of synaptic transmission by clustering of synaptic vesicles