Details of the Optogenetic System
General Information of This Optogenetic System (OS) | ||||||
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OS ID |
OS00729
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OS Name |
Optogenetics system activates by BcWCL1PAS 2
(Opto-BcWCL1PAS 2)
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[1], [2] | ||||
Photoreceptor (PR) |
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Cofactor | Flavin adenine dinucleotide (FAD) | |||||
Controlled Protein | Fusion protein | Activation domain | ||||
OS Application Information (1) | ||||||
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Mechanism of Action | BcWCL1PAS self-dimerization | [ 1] , [ 2] | ||||
Controlled Signal Pathway | Transcription | |||||
Effect | Activation | |||||
Application | Transcriptional activation in yeast | |||||
Note | BcWCL1PAS AD can reach higher levels of transcriptional activation than those obtained with commonly used ADs | |||||
Light Information | Activation Wavelength | Blue | ||||
Process | Reversible | |||||
Deactivation Wavelength | Dark | |||||
Activation Time | 2 h | |||||
Expression Information | Expression Method | Transformation | ||||
Cell Lines | Yeast | |||||