| OS Application Information (1) |
| Mechanism of Action |
pdDronpa1-pdDronpa1(N145K) dissociation
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[
1]
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| Controlled Signal Pathway |
Raf1 activation |
| Effect |
Activation |
| Application |
Use light to regulate Raf1 activity |
| Note |
pdDronpa insertion may be a versatile method for optobiochemical control beyond kinases |
| Light Information |
Activation Wavelength |
500 nm
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| Process |
Reversible
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| Deactivation Wavelength |
400 nm
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| Activation Time |
1-2 min
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| Deactivation Time |
3 s
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| Light Intensity |
20 milliwatts per square centimeter(500nm)10 milliwatts per square centimeter(400nm)
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| Expression Information |
Expression Method |
Transfection |
| Cell Lines |
HEK293T cells |
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