General Information of This Controlled Protein (CP)
CP ID CP00437
CP Name Peroxisomal import receptor (Pex5)
CP Type Recruited protein
Common Name PEX5-related protein (PEX2-related protein) (PEX5-like protein) (Peroxin-5-related protein) (Peroxisome biogenesis factor 5-like) (Tetratricopeptide repeat-containing Rab8b-interacting protein) (Pex5Rp) (TRIP8b)
Organism Homo sapiens (Human)
UniProt ID Q8IYB4
UniProt Entry PEX5R_HUMAN
KEGG hsa:51555
Function Accessory subunit of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels, regulating their cell-surface expression and cyclic nucleotide dependence.
Sequence
MYQGHMQKSKEQGYGKLSSDEDLEIIVDQKQGKGSRAADKAVAMVMKEIPREESAEEKPL
LTMTSQLVNEQQESRPLLSPSIDDFLCETKSEAIARPVTSNTAVLTTGLDLLDLSEPVSQ
TQTKAKKSEPSSKTSSLKKKADGSDLISTDAEQRGQPLRVPETSSLDLDIQTQLEKWDDV
KFHGDRNTKGHPMAERKSSSSRTGSKELLWSSEHRSQPELSGGKSALNSESASELELVAP
TQARLTKEHRWGSALLSRNHSLEEEFERAKAAVESDTEFWDKMQAEWEEMARRNWISENQ
EAQNQVTISASEKGYYFHTENPFKDWPGAFEEGLKRLKEGDLPVTILFMEAAILQDPGDA
EAWQFLGITQAENENEQAAIVALQRCLELQPNNLKALMALAVSYTNTGHQQDACDALKNW
IKQNPKYKYLVKSKKGSPGLTRRMSKSPVDSSVLEGVKELYLEAAHQNGDMIDPDLQTGL
GVLFHLSGEFNRAIDAFNAALTVRPEDYSLWNRLGATLANGDRSEEAVEAYTRALEIQPG
FIRSRYNLGISCINLGAYREAVSNFLTALSLQRKSRNQQQVPHPAISGNIWAALRIALSL
MDQPELFQAANLGDLDVLLRAFNLDP
Optogenetic System (OS) Controlling This CP
OS00205
OS Info
OS Name
Optogenetic regulation of peroxisomal protein import system
[1]
Photoreceptor (PR) Name
LOV2 domain of Avena sativa Phototropin 1 (G528A; N538E) (AsLOV2 (G528A; N538E))
PR Info
Components
Photoreceptor
LOV2 domain of Avena sativa Phototropin 1 (G528A; N538E) (AsLOV2 (G528A; N538E))
Cofactor
Flavin mononucleotide (FMN)
References
1 Optical Control of Peroxisomal Trafficking