General Information of This Controlled Protein (CP)
CP ID CP00411
CP Name Phytochrome interacting factor 3 (PIF3)
CP Type Recruited protein
Common Name Transcription factor PIF3 (Basic helix-loop-helix protein 8) (AtbHLH8) (bHLH 8) (Phytochrome-associated protein 3) (Phytochrome-interacting factor 3) (Transcription factor EN 100) (bHLH transcription factor bHLH008)
Organism Arabidopsis thaliana (Mouse-ear cress)
UniProt ID O80536
UniProt Entry PIF3_ARATH
KEGG ath:AT1G09530
Function Transcription factor acting in the phytochrome signaling pathway. Activates transcription by binding to the G box (5'-CACGTG-3'). Acts as a negative regulator of phytochrome B signaling. Represses chlorophyll biosynthesis and photosynthesis in the dark. Recruits the histone deacetylase HDA15 to the promoters of chlorophyll biosynthetic and photosynthetic genes. HDA15 represses their transcription by histone deacetylation. Promotes the expression of MDP60 to modulate hypocotyl cell elongation in response to light and ethylene signaling. Required for submergence-induced and ethylene-dependent underwater hypocotyl elongation.
Sequence
MPLFELFRLTKAKLESAQDRNPSPPVDEVVELVWENGQISTQSQSSRSRNIPPPQANSSR
AREIGNGSKTTMVDEIPMSVPSLMTGLSQDDDFVPWLNHHPSLDGYCSDFLRDVSSPVTV
NEQESDMAVNQTAFPLFQRRKDGNESAPAASSSQYNGFQSHSLYGSDRARDLPSQQTNPD
RFTQTQEPLITSNKPSLVNFSHFLRPATFAKTTNNNLHDTKEKSPQSPPNVFQTRVLGAK
DSEDKVLNESVASATPKDNQKACLISEDSCRKDQESEKAVVCSSVGSGNSLDGPSESPSL
SLKRKHSNIQDIDCHSEDVEEESGDGRKEAGPSRTGLGSKRSRSAEVHNLSERRRRDRIN
EKMRALQELIPNCNKVDKASMLDEAIEYLKSLQLQVQIMSMASGYYLPPAVMFPPGMGHY
PAAAAAMAMGMGMPYAMGLPDLSRGGSSVNHGPQFQVSGMQQQPVAMGIPRVSGGGIFAG
SSTIGNGSTRDLSGSKDQTTTNNNSNLKPIKRKQGSSDQFCGSS
Optogenetic System (OS) Controlling This CP
OS00600
OS Info
OS Name
Llight-inducible organelle-targeting system
[1]
Photoreceptor (PR) Name
Residue1-908 of Phytochrome B (PhyB (1-908))
PR Info
Components
Photoreceptor
Residue1-908 of Phytochrome B (PhyB (1-908))
Complementary Protein
Phytochrome interacting factor 6; PIF6 (PIF6)
Cofactor
Phycocyanobilin (PCB)
OS00542
OS Info
OS Name
Optogenetic bind and release biomolecules trap
[2]
Photoreceptor (PR) Name
Residue1-650 of Phytochrome B (PhyB (1-650))
PR Info
Components
Photoreceptor
Residue1-650 of Phytochrome B (PhyB (1-650))
Complementary Protein
Phytochrome interacting factor 6 (PIF6)
Cofactor
Phycocyanobilin (PCB)
References
1 A light-inducible organelle-targeting system for dynamically activating and inactivating signaling in budding yeast
2 Generic and reversible opto-trapping of biomolecules