Details of the Controlled Protein

General Information of This Controlled Protein (CP)
CP ID CP00303
CP Name Regulatory protein GAL4 (Gal4)
CP Type Fusion protein
Common Name Regulatory protein GAL4
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
UniProt ID P04386
UniProt Entry GAL4_YEAST
KEGG sce:YPL248C
Function This protein is a positive regulator for the gene expression of the galactose-induced genes such as GAL1, GAL2, GAL7, GAL10, and MEL1 which code for the enzymes used to convert galactose to glucose. It recognizes a 17 base pair sequence in (5'-CGGRNNRCYNYNCNCCG-3') the upstream activating sequence (UAS-G) of these genes.
Sequence
MKLLSSIEQACDICRLKKLKCSKEKPKCAKCLKNNWECRYSPKTKRSPLTRAHLTEVESR
LERLEQLFL
Optogenetic System (OS) Controlling This CP
OS00052
OS Info
OS Name
Photoactivatable Gal4 for transcription activation by Cryptochrome 2
[1]
Photoreceptor (PR) Name
Cryptochrome 2 (CRY2)
PR Info
Components
Photoreceptor
Cryptochrome 2 (CRY2)
Complementary Protein
Cryptochrome-interacting basic-helix-loop-helix 1 (CIB1/CIBN)
Cofactor
Flavin adenine dinucleotide (FAD)
References
1 Bidirectional approaches for optogenetic regulation of gene expression in mammalian cells using Arabidopsis cryptochrome 2