Details of the Optogenetic Tool

General Information of This Photoreceptor (PR)
PR ID PR00161
PR Name Improved Light-Inducible Dimer (iLID)
Source of Species Avena sativa
Class LOV domain
UniProt ID O49003
GenBank 747155673
PDB ID 4WF0
Sequence
LATTLERIEKNFIITDPRLPDNPIIFASDSFLQLTEYSREEILGRNCRFLQGPETDRATV
RKIRDAIDNQTEVTVQLINYTKSGKKFWNVFHLQPMRDYKGDVQYFIGVQLDGTERLHGA
AEREAVCLIKKTAFQIAEAANDEYNF
Components Photoreceptor Improved Light-Inducible Dimer (iLID)
Complementary Protein Stringent starvation protein B (SspB (R73Q))
Detail Info
Cofactor Flavin mononucleotide (FMN)
Detail Info
3D Structure
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Complementary Protein Detail of This PR
Complementary Protein Stringent starvation protein B (SspB (R73Q))
UniProt ID P0AFZ3
Sequence
MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPMEYARDGQIVLNIAPRAV
GNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGTMFEPEAAYDEDTSIMNDE
EASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPALRVVK
Cofactor Detail of This PR
Cofactor Name Flavin mononucleotide (FMN)
PubChem CID 643976
Structure
Formula C17H21N4O9P
Molecular Weight 456.3
Optogenetic System (OS) Consisting of This PR
OS00354
OS Info
OS Name: Light regulated signal protein localization and activity system 3 (LRPLA 3)
[1]
Functional protein: Improved Light-Inducible Dimer
Detail Info
Recruited protein: Stringent starvation protein B
Detail Info
OS00355
OS Info
OS Name: Light regulated signal protein localization and activity system 4 (LRPLA 4)
[1]
Functional protein: Improved Light-Inducible Dimer
Detail Info
Recruited protein: Stringent starvation protein B
Detail Info
References
1 Engineering an improved light-induced dimer (iLID) for controlling the localization and activity of signaling proteins