Details of the Optogenetic System

General Information of This Optogenetic System (OS)
OS ID
OS00688
OS Name
Light-responsive RNA-protein nanowires (LRNA)
 [1]
Photoreceptor (PR)
PR Info
PR Name
LOV2 domain of Avena sativa Phototropin 1 (AsLOV2)
Source of Species
Avena sativa
Class
LOV domain
UniProt ID
O49003
GenBank
162330142
PDB ID
2V1A
3D Structure
Components
Photoreceptor: LOV2 domain of Avena sativa Phototropin 1 (AsLOV2)
Cofactor: Flavin mononucleotide (FMN)
Cofactor Flavin mononucleotide (FMN)
Controlled Protein Functional protein LOV2 domain of Avena sativa Phototropin 1
Detail Info
Recruited protein Zdark
Detail Info
OS Application Information (1)
Mechanism of Action LOV2-ZDK disassemble [ 1]
Effect Sensor
Application Form and disassemble RNA-protein nanowires
Note This RNA-protein hybrid biomaterial does not rely on the photochemistry commonly used for light-responsive biomaterials, such as bond formation, cleavage, and isomerization
Light Information Activation Wavelength 450470 nm
Process Reversible
Deactivation Wavelength Dark
Activation Time 15 min
Deactivation Time Seconds to Minutes
Expression Information Expression Method Transformation
Cell Lines .
References
1 Engineer RNA-Protein Nanowires as Light-Responsive Biomaterials